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Our Research
General research areas in the Barbie lab include:
Understanding mechanisms of pathologic innate immune signaling and its relation to oncogenesis in lung cancer
Targeting KRAS mutant cancer
Elucidating the role of the cGAS-STING pathway in lung cancer
Developing predictors of response to novel targeted and immune modulating cancer therapies
Building advanced 3D ex vivo tumor culture technologies to study immune responses in cancer
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