Our Research

General research areas in the Barbie lab include: 

• Understanding mechanisms of pathologic innate immune signaling and its relation to oncogenesis in lung cancer
• Targeting KRAS mutant cancer
• Elucidating the role of the cGAS-STING pathway in lung cancer​
• Developing predictors of response to novel targeted and immune modulating cancer therapies 
• Building advanced 3D ex vivo tumor culture technologies to study immune responses in cancer